My Python isn't very good so I'm not familiar with your cxFreeze/pyOxidizer/pyInstaller list, but couldn't you just develop your python using one of these tools from the start?
For instance, if you do ML, then you use NumPy, Scikit-Learn etc. It's all C / C++ code, which you will have to link with somehow. And even if you figure out how to link with it, your program will still suck because of the unnecessary (as I call it) PyObject layer, i.e. the Python interpreter interface that is used for communicating between Python libraries. Eg. say you wanted to pass a pointer from one library to another. If you were writing in C -- no big deal, just have some externally visible function in one library and call it in another, and you are done. But if you want to connect two Python libraries, at best, you'll have to use a special struct PyCapsule, with two dozens or so of fields, which is allocated by Python's allocator and also needs to be deallocated... The overhead will be tremendous.
Similarly, if you do Web development, you need some HTTP server that can run fast. I haven't touched this part of Python in a long time, but the last thing I came to use was Tornado, which was a C library with Python bindings.
When it comes to infra, there are plenty of tools that are also written in C, various database drivers, Kafka client, encryption library... and so on.
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Bottom line, even if you defeat the system and manage to make it all compile together... it won't work well, not as well as it could have if only you could ditch Python entirely from this equation. And if you could, then... well... you'd be just writing in C...
"Python is a shit language because it doesn't do/have [insert a niche thing that you think a language should do]"
Which is failing to grasp the role Python plays. You can make this sort of argument against any language, and generally you would be correct in the fact that languages can be improved.
But the fact remains that Python is widely used, and no, its not because people are dumber than you and don't know better, its because they simply dgaf about any of the niche cases you talk about.
For example, nobody is going to look at Numpy and realize its C, and ask the question of "Hmm, I wonder why Im using Python in the first place if its really just C under the hood". Not to mention that the practice of patching Python libraries through C like you describe pretty much never happens. Not to mention that core ML isn't even the standard C, its open cl or CUDA C which are specialized, and how you get to defining those kernels is largely irrelevant for functional sake, but largely relevant in how efficient and simple it is, which is why Python is used.
For all your other issues across comments (like venv, pip dependency), you seem to assume that when someone runs into the issue, it somehow causes everything to break and things to fail. None of what you describe really plays out in reality on a large scale. Things work because people are smart enough to realize what they are doing. It could be that you personally have issues with your company, which is the source of your frustration, but I can assure you that is not the case across all of industry. Google, despite its many issues, has built plenty of good things using Python, and defaulting to C/C++/Go when they need to.
Google, despite its many issues, has built plenty of good things using Python, and defaulting to C/C++/Go when they need to. When you start building better things than Google in other languages and prove that the thing is better because of the language choice, then you will have a point.
In your reply to my other comment, you said
"But, even, imagine that in your fairy-tale world Python is somehow so super-important and successful? Didn't I already explain how this is possible while still being a garbage language?"
This is the equivalent of you just standing in the middle of the busy street with a sign that says "everyone is on a path to hell with your choices in life, you must repent and follow Jesus". You are entitled to your opinion, but I hope you realize that you aren't making any real points.