No. The kinetic energy of the car/bike/… doesn't tell you anything because you don't know how much energy gets transferred to the victim until you have applied momentum conservation to the elastic/inelastic problem. So, the right approach would be (in this order): Calculate momenta, calculate how much momentum gets transferred to the victim via momentum conservation, deduce the resulting change (increase) in kinetic energy of the victim. This kinetic energy will be converted into heat (= damage/injuries) in one way or another, so it's the relevant physical quantity for our considerations.
Finally, in case of an inelastic problem (likely with cars, not so likely with bikes or people), you also need to consider the energy loss during momentum transfer. Once again, this energy will become heat (= do damage), so it adds to the aforementioned increase in kinetic energy when we're interested in how much damage will be done.