Um, that is exactly what I did with my last fridge. I went to the appliance store, and got a $30 discount for cash & carry. Backed my F150 up to their warehouse, loaded it up, and drove it home.

Now I don't buy a fridge everyday, but I've had to get enough large items over the last 10 years for the house to make the pickup truck worth it (when I first got the truck I was picking up some 2x4s, couple sheets of drywall, etc, about every couple weeks -- finished the basement, built a shed, etc, buy buying a couple pieces at a time).