A woodworking clamp with a handle in line with the screw will generate about 400lbs of force. That’s a reasonable model for how much axial force you will be able to exert with a screwdriver handle and beefy threaded screws. To get 150000 psi you have to squeeze something .0027 square inches, or 1.7mm^2, leave some room for edges and let’s work with 1mm^2.

I’m not sure what interesting things can be done with this superconductor in 1mm^2, but squeezing the anvil isn’t outrageous.

For perspective, TSMC will put 150 million transistors in that area. I kind of suspect that integrated circuits might flow at this pressure, so that might not be the application, but a superconducting ground plane and power plane would be interesting.

Edit: Wait, maybe that’s just a giant capacitive load on all the signals. Do something smarter.