If anyone wants to add this Ocaml engine to the harness (or any other engine), please email me at jamslam@gmail.com and I'll give access to the repo. The only reason it isn't public yet is because I'm still working on the initial release and iterating. But it's close enough where other people could submit benchmark programs for other regex engines.
It's actually easy to compute classes of characters that have the same derivative (it's done in the linked "Regular-expression derivative re-examined" paper, although their particular implementation favors simplicity over efficiency), and it's not even necessary when using Antimirov's partial derivatives.
Actually, the complexity of the derivation is independent of the size of the alphabet. You could even define derivation on an arbitrary semi-lattice, not necessarily a set of characters. (Or a boolean algebra if you care about negation/complementation).
The difficulty in handling unicode has more to do with the efficiency of the automaton representation and manipulation rather than in turning the RE in an NFA or DFA.
It has been a long time since I read the "Regular-expression derivative re-examined" derivative paper. Mostly the only thing I remember at this point is that I came away thinking that it would be difficult to adapt in practice for large Unicode classes. But I don't remember the details.
It is honestly very difficult for me to translate your comment here into an actionable implementation strategy. But that's probably just my inexperience with derivatives talking.
I don't know any besides ocaml-re that Drup already linked, sorry :).
And sorry that my comment is hard to decipher. I think the core point is that the "character set" can be an abstract type from the point of view of the derivation algorithm. So it doesn't matter how they are represented, nor "how big" a character set is.
With Antimirov's derivative (which produces an NFA), there is no constraint on this type.
With Brzozowski's derivative, you need at least the ability to intersect two character sets. So the type should implement a trait with an intersection function (in Rust syntax, `trait Intersect fn intersect(self, Self) -> Self`). That's necessary for any implementation generating a DFA anyway.
And if you also want to deal with complementation, then a second method `fn negate(self) -> Self` is necessary.
I do wonder if there is some room for derivatives in a meta regex engine (like RE2 or the regex crate). For example, if it let you build a DFA more quickly (in practice, not necessarily in theory), then you might be able to use it for a big subset of cases. It's tricky to make that case over the lazy DFA, however, a full DFA has more optimization opportunities. For example, identifying states with very few outgoing transitions and "accelerating" them by running memchr (or memchr2 or memchr3) on those outgoing transitions instead of continuing to walk the automaton. It's really hard to do that with a lazy DFA because you don't really compute entire states up front.