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I don't think this holds. Such freak mutations happen all the time.
Note that this doesn't discredit lab leak either. It's entirely possible they were testing a new, entirely natural strain they found in some weird cave somewhere. And because that lab had terrible safety protocols (which has been documented extensively), possibly some got out.
It's not really possible to rule out or confirm the lab leak hypothesis without inside information that we are unlikely to ever get. Other than as vague "intelligence report says this", which you can hardly trust.