And then you "just" have the same problems that you have with purely electrically connected, analogue speakers (which are effectively 100% in sync in terms of receiving the signal): Sound is relatively slow, and so the audio from a speaker that is far away will reach you later than the nearby speaker.
You can mitigate that by adding a precise delay to the far away speaker... but of course that does not work if you're standing on the other side. Nevertheless, as said, that problem is regardless of whether your speaker is network-connected or not.