Not at all short term. This is EXACTLY what fasting is. In fact a pill you could take in the morning that would suppress your appetite for 24 hours would be fantastic. You could use it three days a week with no ill effects and loose weight.
The comment I was replying to was talking about Mounjaro, which is a weekly injectable - and thus no way to do it for only three days a week. In that context, if Mounjaro made it impossible to eat to the degree the commenter described, it would be wildly unsafe (because of how long each shot lasts).