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Not at all short term. This is EXACTLY what fasting is. In fact a pill you could take in the morning that would suppress your appetite for 24 hours would be fantastic. You could use it three days a week with no ill effects and loose weight.

True.

The comment I was replying to was talking about Mounjaro, which is a weekly injectable - and thus no way to do it for only three days a week. In that context, if Mounjaro made it impossible to eat to the degree the commenter described, it would be wildly unsafe (because of how long each shot lasts).

This is not an exaggeration for my wife. For a full day after taking her weekly shot, she eats about 2 bites per meal.

The first three days were like this.