Lit gives you reactive components, declarative HTML templates, runtime encapsulated DOM and styles, interoperability with frameworks and HTML via web components, and a lot more - with no required build tools at all.
We take great care to make sure our libraries are usable without build tools. We support plain JS (in addition to TypeScript). Our libraries work straight from CDNs like Unpkg. When installed locally you can use a dev server that rewrites bare module specifiers or use an 8-line import map to make all of our core packages importable (we carefully keep all of our import specifiers compatible with the web and compact import maps). Components are inspectable with regular DevTools. You can even write components right in DevTools, or in a script tag in plain HTML.
I honestly wish this weren't a unique selling point of Lit, but as far as I can tell, of the "major" frameworks or component libraries out there (including React, Vue, Angular, Solid, Ember, Svelte, Stencil, Preact, and more) we're the only ones that fully work with plain JS within our regular mainstream usage patterns.