I don't have the stats, but AD blockers & tracking blockers are a real spanner in the works for AD-Tech. I imagine blocker popularity exponentially increases as each year passes, meaning at some point they will make a substantial dent in AD-supported sites who rely on income from ADs to stay online.
Google has so much data on people they can essentially read people's minds, so they are doing fine in regards to targeting people properly. They have a tight ship and it works (For now). Same for Facebook, although Apple's tracking opt-out apparently is hurting their business.