As I've mentioned frequently before, it amazes me how many people looking at tech company financials will only look at Revenue and completely ignore profits.
What the revenue/profit plot you showed for TWLO clearly demonstrates is that there is no magic point there suddenly you increase revenue and profitably starts to increase as well. I think an assumption many people have is "if revenue keeps rising you have to be profitable soon", clearly that is not always the case.
Another pattern I've noticed is that many companies are not like Amazon, which is the model of a growth company. While AMZN does often reinvest its profits (historically to the dismay of investors) it has repeatedly demonstrated that it can be profitable. For companies like TWLO and UBER it's not obvious that they even can be profitable.
When I see this TWLO chart the message I get is that the only way to increase revenue is to increase net losses. It's not even remotely clear that TWLO can generate a profit at any level of revenue.