I get that perspective. There aren't a lot of people who agree with my risk assessment. I'm _mostly_ not going to tell other people what they should or shouldn't do (I do wish we'd go back to universal masking in a few locations, like doctors offices and government buildings. Higher risk and more cautious people can avoid restaurants and bars, but you can't just not show up if you get summoned for jury duty, or need to get treated for cancer).
Ultimately, either I'm wrong and the opportunity cost is the extra years of quality I'm losing to continued caution, or other people are wrong and the cumulative effects of infections are going to greatly impact their quality and quantity of life. If everyone chose to take some extra precautions, like masking, better ventilation, and staying home when they were sick then I'd have to give up less, and other people might not be risking so much, but I know that's just not going to happen, and I'm going to deal with the world as it is rather than as I think it ought to be.
My guess is that, although covid isn't going away, in a few years I think things will improve. Long covid is real, and it's having a real economic impact already. It's going to have a bigger impact in the coming years, and there's going to be real incentive to do something about it when it becomes clear that it's a huge drag on productivity. Prophylactic nasal sprays, better post-exposure protocols, next generation vaccines, faster and more reliable testing (preferably something that detects covid in the air rather than relying on individual testing), improved ventilation- all of that is being worked on, and I think eventually a lot of things will be low enough risk that I'll resume some activities.
In the mean time, I'm lucky to be far enough in my career that the impact of a harder line stance on this isn't too bad. Technical collaboration has always been largely remote for me, and there are ways I'm able to maintain connections with friends and family even though we rarely see each other in person.