qwik may be appealing technically, but it's not the best fit for web applications because:

1. You're required to use qwik's API for React, limiting your flexibility and hiring.

2. The lack of compatibility with the vast React components and libraries ecosystem means you'll have to start from scratch on all your components, even essential ones like calendars, MaterialUI, charts, etc...

If your focus is on creating a website and try something else than say Gatsby, then qwik may be a good option. However, for web applications and the ability to fully utilize the React ecosystem, it doesn't seem to be the best choice.