Assuming it could be done, I think you'd activate the reservoir, then bombard the patient with anti-retrovirals until the virus was eradicated?
The point is, in the presence of a retrovirus with its reverse transcriptase trickery, an organism is a chimera, populated by dna-distinct cells (for example, never infected cells vs cells previously infected and thereby holding modified dna, who would send out new virus during their own replication).
If this same mechanism kept infected cells from remaining latent, eventually you would clear the virus.
So I don't know the answer to your question, but my answer was assuming an answer existed :)
This is from the top of my had, I’m not an expert in the field.
With thymus involution?
People often confuse an "outbreak" with "massive infection".