I've worked with hundreds of scientists from different domains over the past two decades and I've literally never once heard of wanting to use Javascript for anything remotely scientific.
Furthermore, given that WebAssembly seems poised to (eventually) make strides in how browser-oriented applications are built then the logical conclusion is a sort of reduce function on languages where you choose the language that's the most pleasant to write and maintain since you will eventually be able to just target the browser from anything. For the life of me, I can't see a future where large, STEM-educated groups and agencies decide "Well yeah, I guess if we can use this cooked-in-a-weekend piece of $^&# then why would we ever use Python?"
I think a lot of language enthusiasts see python projects entering into spaces where it wasn't previously viable and think that the same principle applies to their language, which misses something fundamental about why Python has so deeply entrenched itself into the STEM/ML world, and why it will NEVER be uprooted. When I see things like Brython/Pyscript/Pyodide, it's obvious to me that people would rather write Python for ~accomplishing the task they set out to~ than have to muck around with another language entirely. Python is a winner in so many spaces because of that element of taking the programmer from Point A to Point B the easiest way. It's a language designed for accomplishing tasks, for getting stuff done, for being understood at a glance. Javascript was made up by one guy, in a very short period of time, for a singular purpose that it didn't even do well when it was introduced and has stuck around due to sheer coincidence and convenience. All languages on a long enough timescale converge to a point of usefulness but if we're pitting Python against JS I just can't see the scales tipping enough to warrant choosing it for real work.