No, different kinds of drugs are different in kind.
I've never met anybody who takes MDMA to feel normal. Most people I know who use it do so once or twice a year and carry lessons from that experience that make sober life better.
Molly taught me to let myself dance, for instance. Or to joke around with strangers.
Sure, people who do it every weekend have a degraded sense of normal after a while, but that's not just an amplified stage of normal use, it's damage to their ability to regulate serotonin. Friends don't let friends do that to themselves.
Unhealthy usage patterns of other drugs may cause damage to other systems depending on which systems those drugs activate (e.g. dopamine, gaba, opoid, etc) but if a different system is damaged it's different in kind and not degree.
This all-drugs-are-more-or-less-the-same narrative is dangerous. You learn that drugs are bad (thanks D.A.R.E.), and then you learn that part of that was a lie.
What's a curious person to do next except try them all?
As for the non-curious, if you go around with an all-drugs-bad attitude and don't have and idea of what healthy usage looks like (because the healthy users are keeping it a secret from you), you're unavailable to help course correct a friend whose usage has started to become problematic. By the time the problem is so bad that they can't hide it anymore, the ideal time to speak up will have long since passed.