I think Dvorak is the only alternate the makes sense to use because it's supported most places. You can easily get a new device and set it for Dvorak. Anything else and you are now Googling for guides. I have Dvorak on my Mac, iPhone, Windows, and Chromebook. If I have to help a co-worker on their machine I can quickly switch it over.
That said I will not purport that Dvorak is better in any technical way that the other alts.
For me the switch was to force me to break my bad typing habits and learn to touch type.