A couple centuries ago, the brightest minds thought that humans flying in the air would take a million years. How can humans travel to the other part of the earth within a month? Today, it takes 16 hours (4 of which are airport security).
A century ago, almost everyone thought that stepping on a divine body like the moon is absolutely impossible for humanity. We did it less than 80 years after inventing aircrafts.
A century ago, everyone thought it was impossible to fling a tiny device to blow up an entire city. Hiroshima and Nagasaki...
Now, we think that it would be impossible to travel very long distances in space. Well, this challenge seems a piece of cake compared to flying in the air, walking on the moon, or generating unimaginable energy from atoms.
My layman solution to interstellar travel is constant acceleration using controlled nuclear fusion. We can use interstellar dust for necessary matter for our nuclear fusion (lots of hydrogen in interstellar dust). Even if we can't use interstellar dust while travelling, we can certainly carry enough from our solar system.
I read somewhere (don't remember where) that if a ship constantly accelerates in space, it can reach another star system in a few decades and another galaxy in less than a century.
It's definitely a trivial challenge for humanity compared to what we have accomplished in the last 2 centuries. What do you think?