I idly played with BTC one evening and I let it mine for about a week or so on a fairly poky PC and got bored of it eventually. I was more interested in Folding@Home.
As it turns out I was both right and wrong. That BTC was going to be worth up to $64,000 at one point in time. However, protein folding might save lives.
I ditched that PC and didn't copy over the wallet because I'd forgotten about it - it wasn't that important. I am very aware now that it would probably be a good idea to back up things like that 8)