Is anyone attempting to harm-reductively try meth?
Is anyone attempting to harm-reductively try meth?
[0]: https://astralcodexten.substack.com/p/know-your-amphetamines
Now, if the difference between a “left-handed” and “right-handed” meth molecule can be so great, it shouldn’t come as a surprise that adding a methyl group to regular amphetamine will change its effects considerably.
This can be seen in the different receptor binding profiles (which receptors, where in the brain, and how strong or long the modulation is).
Meth’s increased addictive and neurotoxic effects are owed to this difference in receptor binding.
https://www.ktvu.com/news/san-francisco-supervisor-drug-over...
The “harm reduction” websites are full of information about things like: Dose ranges for beginners, what effects to expect at different dose levels, routes of administration, and so on.
This information is targeted at beginners or drug curious people.