I see 3 steps: a) Mac Studio, b) MacPro with PCI/MPX modules, c) Dedicated HW boxes.
I think the size of the step between a and b is becoming too small to be viable: not enough extra performance, and too high price compared to step c.
Dedicated HW boxes connected using Ethernet/Thunderbolt/USB-C have the great advantage that you are no longer bound to whatever Apple offers this year. You will just use the Mac/Windows as a "advanced graphical terminal".
Same for hardware developers. Looking back at the past 10 years of MacPro shows great uncertainties in what Apple offers going forward. Why would you spend time making a PCI card for MacPro when Apple so easily abandons support for PCI with the TrashCan while you could have a reliable market with a thunderbolt/ethernet accessory?