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Maybe... "Are you mentally handicapped" sounds more insulting to me than "Are you retarded" but maybe it's from playing video games too much

Oh, don't worry, children are infinitely inventive and will make a slur out of that too, given enough time.

You can't stop the euphemism treadmill.

The irony, since retard was chosen as a gentle way of saying "slow".

Mabye you're right, more syllables, less catchy.