Do you remember when there was a tiny blip in production for COVID, and suddenly the shelves were empty? What do you think is going to happen if 100 nukes go off and wipe out strategic chunks of the USA?
In the Midwest, supply shortages of staples and most consumer goods were not so bad that the "shelves were empty."
You might have had to buy a different brand of a given good.
The only real annoying thing has been products that use semiconductors.