If there was ever a title which needed a native Linux build, this is it. ProtonDB does not list compatibility yet, have any of you tried?
I was personally able to download on Linux (Pop!OS) and run it without enabling proton experimental or installing anything else. Worldbuilding didn't seem noticably longer than classic.
[1] https://www.gamingonlinux.com/2022/11/dwarf-fortress-release...
https://github.com/bottlesdevs/wine/releases/tag/caffe-7.20
Then you can drop that into the default folder in Lutris and choose it as the runner. Lutris also integrates with Steam so it'll see your entire steam library and you can choose a different wine runner and wine options on a per-game basis.