Not necessarily, there are other possibilities, for example the mechanism might not be lack of male hormones, but elevated female hormones, or environmental contaminant analogs thereof.
The hormone panel is typically T,E1,E2, but human hormonal pathways are complex[2] and not fully understood. There are, for examples, hypotheses involving "backdoor" pathways that should/could be verified, but aren't due to lack of research funding directed toward an admittedly small group of people.
1. That's not to say all or even most, but it is very very common.
2. https://en.wikiversity.org/wiki/WikiJournal_of_Medicine/Diag...
How well documented is this, like when this has been tried has it been done as part of a formal medical study? What I'm really hoping is someone can say something like "here's the randomized controlled trial comparing treatments".
Could that be explained by the unfortunate lack of trans acceptance?