If someone (for example) got Apple's iOS signing key and Apple's HTTPS certificate, Apple could suffer catastrophic damage. If someone got the PlayStation 5 signing key or the Xbox One signing key, catastrophic damage there. In a way, it's a beautiful, super-secure house... built on a single ludicrously powerful point of failure. Good thing we don't have any corrupt government agencies who might want to bribe someone for keys... yet... hopefully...
This is actually something I would fear for the future. There have been countless physical heists - most recently in Antwerp, Belgium, where over $100 million in diamonds were stolen in 2003. We haven't had a major signing key stolen yet, but there's always that first day... if you can't keep $100M in diamonds safe, can you really be sure that you can keep a hardware signing key safe forever? Heck, the logistics of stealing the diamonds is insane - but stealing a key only takes a pencil and a piece of paper.