WasmEdge is one of the most exciting Wasm runtimes out there. It is part of the CNCF and does support a bunch interesting functionality (wasi-nn, integration with Docker via runwasi, etc)
The benefit of using Wasm as a wrapper is its high performance (Use Rust to prepare data) and multi language support (inference in JS!)
WasmEdge supports Tensorflow, PyTorch, and OpenVINO as wasi-NN backends.