I think the comparison is facile. I'm just a layman, but it is my strong impression that nearly all scientists working at the edge of astrophysics and quantum theory know what they have is a model, sometimes stunningly predictive and accurate but still a model. The vast majority of experimentalists (and theorists) would love to get some result that is inexplicable, far more than another experiment that takes years and doesn't turn up any surprises. Dark matter, dark energy -- as far as I know, everyone working on them see our current ideas as placeholders until someone comes up with a good explanation.
Sure, there are many examples of scientists clinging on to old ideas too long, but eventually when enough evidence is marshaled by someone to overturn the old model, they are heralded and given honors.
That is all to say: frontier physics is utterly unlike religion, where so may claim to KNOW the truth, where the most tenuous claims are literally gospel, where there is little desire admit counter-evidence.