Rule number one at startups: write things that don’t scale and use mature, boring frameworks/languages.
The goal is to deliver products and iterate as fast as possible. Productivity is key to success.
IF (and it is a big IF) your startup ever gets to the point of having to scale up (nice problem to have) then just throw money at AWS, hire senior engineers and let them figured it out.
What matters is customer experience; nobody cares of what’s behind the scene.