No, actually. These days there are very few non-generic pieces. If we're talking bionicles, then yes. But 99% of pieces in any modern set (branded or otherwise) are generic. The exception is usually things like fighter windshields (if they're called that in space?).
e.g. The Star Destroyer engines are actually wheels presumably borrowed from some other set. The Death Star as far as I can tell has no "special" pieces, nor the AT-AT, AT-ST or X-wing. The millenium falcon has a few special bits, but even they look repurposed from some other set.