Leonhard Euler:
Born: 1707
completes masters in philosophy: 1723
lost vision in right eye: 1735
Solved 7 bridges problem: 1736
publish Introductio in analysin infinitorum, volume 1: 1748 [2]
Euler-Bernoulli Beam Theory: 1750
Euler's Formula (geometry): 1750 [1]
publish Institutiones calculi differentialis: 1755 [2]
near total blindness: 1766
publish Theoria motuum lunae: 1768
[1] http://www.ics.uci.edu/~eppstein/junkyard/euler/
[2] http://eulerarchive.maa.org/historica/euler-timeline.html
There's plenty more that's left out. After his near-total blindness, he averaged publishing one mathematical paper per week in 1775. To assume you or I are like Euler is hubris. To assume otherwise is doing a disservice to humanity.