It's the moral equivalent of making major headway against P!=NP; or, proving that there are no global hidden variables in QM; or, that there's a clear path ("just engineering") to room-temperature semiconductors.
I suppose superconductors. Semiconductors are well in the room temperature regions :)
If you think that prime numbers are interesting, then I can tell you that GRH is the single most central conjecture in the study of prime numbers. Personally, I think prime numbers are some of the most fundamental and intrinsically interesting objects in pure math, but of course, this is subjective!
what would be an example of "deep philosophical" implication that has no bearing on the "nature of reality"