What should make people more comfortable
that Germany will be able to safeguard
against their known risks?
The safety of nuclear power plants isn't exactly some great unknown.There are ~450 plants currently operating in the world, with an average age of multiple decades. Plus all the ones that have been retired. That's a lot of data.
You don't really have to take anybody's word for it. They're safe.
They are not zero-risk, because literally nothing is. We also absolutely know the risks of fossil fuels (the planet is burning, and buyers potentially become dependent on hostile countries like Russia) and the current limitations of renewable energy sources.
So, to answer your questions: that is how you judge their potential safety in Germany or anywhere else.