1. For the first time, people are also willing to be violent against the regime.
2. This is more geographically distributed than previous ones.
3. It's distributed among all classes now.
4. It has been going the longest, despite the violence of the regime.
I think this is definitely the first time since the Green Movement that the regime is really sensing existential threats.
One thing to people watching the news:
This is probably the biggest woman's rights movement in middle east history (or the world). I don't think Woman fought this hard for their freedoms anytime (Could be wrong though). Also probably the biggest secular movement in ME history.
Source: Iranian, used to be part of the green movement, nowadays living in the US only with friends and family in Iran.