Only if the tui doesn’t create pseudoterminals. In 2022, even Windows 10 has them (conpty) and unix has them for like forever (openpty).

Gdb server helps.

Here a quick tutorial from some other HN poster the other day: https://news.ycombinator.com/item?id=33032827

I sometimes run an empty xterm or tmux window and redirect the inferior to it using set inferior-tty