GTA always been "kind of serious but mostly comedy and sarcasm/parody" and RDR always been "This is deadly serious" so the stories will reflect that. I wouldn't assume GTA will have as serious story as RDR2 had.
Again, it'd be super controversial and will probably never get made, but I'd play a game like that.
It has over the top moments (like GTA) but I think the story is compelling and it’s not hard to see the parallels to modern day groups and events.