It’s the underpinnings of many different problems. And think about it for a sec, if you found yourself hypersensitive to cortisol how do you think your brain would react?
Medicine isn't 'think about it for a sec' - you made direct claims using unscientific terms - Cushings is a very specific and relatively rare disease that has no realm of relevance here. Not sure where you are trying to go with this but it is obvious you have no medical background or standing.
And please enlighten me on your medical background / standing. I used to teach stats to doctors to help them understand medical tooling.