They could re-appeal [0] or play some other judicial trick. Or maybe they say "enough is enough" and don't pay it.
They have been appealing the €2.42 billion fine from July 2017 even now[1]. So I don't think that they have any intention to pay this much larger fine any time soon.
Google's stock is already doing bad this year and this will likely make it worse (although the early trading today hasn't shown any indication of a change.)
[0] "The company can still appeal the ruling in the EU’s highest court." - https://www.cnbc.com/2022/09/14/eu-court-backs-antitrust-rul...
[1] https://curia.europa.eu/jcms/upload/docs/application/pdf/202...