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I'm not OP, but I choose the first two. What are your recommendations?

It’s like asking: time, money, or resources? Pick only two

It depends on your goal.

Me; <=2014 CPU, DDR3, Whonix/Gentoo OS with eBPF JIT compiled out for servers;

QubesOS for desktops with bleeding edge CPU, H/T BIOS disabled, and CPU IBT compiled out.

Absolutely no JavaScript (not even WASM).