I really want to put one of these in my Dell Precision workstation, and I share similar concerns. I have an older Quadro in it now and could use a proper upgrade, but I really want to wait for the 4000 series cards due in a few months.

Craft Computing on Youtube has the best information from what I have seen so far. I don't like watching Youtube videos for information like this, but I understand why creators have moved to this medium in general. Linux should be much easier to configure for using the K80 to capacity.