There aren't too many keyboards with a ¢ key included, so I suppose that alone could be a show stopper.
Other languages in former Warsaw Pact tend to have "Programmers" layout available as well, because the national standard layouts tended to be designed for typewriters not programming and lack all kinds of characters people need - unless you go trigram route in C/C++.
For what its worth, Common Lisp at least does let you remap ` and such :)