Having said that, let me say a large extinction event is certainly possible - we may have barely dodged one in the late 1800s:
http://www.theblaze.com/stories/has-the-earth-come-close-to-...
But to plan for something like that we would be better off tunneling into the earth than trying to colonize Mars. The other planets will never be hospitable to human life, and there's no point in bothering with them until we have the technology we need to make the colonies independent. We're a long, long way from that, and sending more rockets to the moon doesn't get us any closer.