That is a good question. I personally am compensating for the lack of nutrients in food and also over-compensating for damage that I have done to my organs from a lifetime of eating a "standard american diet" or what I prefer to call a "first world diet". A healthy food diet just wasn't cutting it for me, especially given that stomach acid and other aspects of digestion decrease with age. I can compensate with digestive enzymes, tudca, benfotiamine and chelated zinc but that has rapidly diminishing effects.

My goals go far beyond what a good diet and moderate exercise and decent sleep alone can accomplish but I would never even try to convince anyone to do what I am doing nor would I even suggest it unless one researches all of the molecules and their downstream effects ad-nauseam.