One example would be the lack of pragmatic rust native GUI libraries. There are wrappers for GTK and Qt, which are probably your best option.
The most popular pure rust ones are based on somewhat esoteric patterns and seem prone to being abandoned.
Within that there are some interesting options, like for functionally reactive programming and immediate mode guis, but these paradigms aren’t all encompassing and in fact cover a pretty minority use case based on what GUIs are being created today.
Maybe one day we’ll all only ever create purely functional GUIs and speak Esperanto, but until then, we’re a little hamstrung in rust.