That has never been thought by anyone but computer scientists who never looked at a biology textbook.

To begin approximating what a lone spherical synapse would actually do you'd need to solve 2^n coupled second order differential equations where n is the number of ions used.

That is before you throw in things like neuro transmitters and the physical volume of a cell. Simulating a single neuron accurately is beyond any super computer today. The question is how inaccurately can we simulate one and still get meaningful answers.

Then how we do it 100e9 more times.