Trans women typically take E2 (bioidentical estrogen), not EE2. EE2 is 100 times more potent than E2 for certain endocrine interactions. Unlike E2, EE2 is not a naturally occurring hormone. E2 causes female puberty when administered to males (except for menstruation), but EE2 isn’t necessarily going to do the same thing because it is a different molecule. While worrying about “feminizing” is probably hype, worrying about possible effects such as infertility seems totally reasonable.