Definitely one of my favorites, too. There's an elegiac quality to it that I haven't quite seen in any other novel.
I have a number of quotations jotted down from it, but since this a tech site I'll restrict myself to sharing this one that I sometimes think of when dealing with a recalcitrant machine or mysterious bug:
"That contraption--listen, Brother, they claim it thinks. I didn't
believe it at first. Thought, implying rational principle, implying
soul. Can the principle of a 'thinking machine'--man-made--be a rational
soul? Blah! It seemed a thoroughly pagan notion at first. But do you know
what?"
"Father?"
"Nothing could be that perverse without premeditation! It must think!
It knows good and evil I tell you, and it chose the later."