The issue is only partly about whether non-sugar sweeteners have negative effects. The more important question is whether regular & processed sugars produce an overall worse impact than substitutes consumed at comparable levels, with stratification by consumption level.
E.g., non-sugar sweeteners may have a similar danger profile at both low and high levels of consumption while sugar's negative impacts may be more linear. Or so other balance. In a situation like that, the proper advice to individuals looking to become healthier may vary, especially given that immediate and rapid wholesale change if a person's behavior is not usually possible.