This was not my experience with TeXmacs. I tried it recently after using LaTeX for all of my papers, and while it is nice, it is not replacing LaTeX for me.

Table output in particular was much lower quality than LaTeX with booktabs. I think I had to manually resize columns, which was tedious, and I never had to do that with LaTeX. There were a lot of similar situations I found myself in, where I wound up needing to fight TeXmacs quite a bit to get it to output what I wanted.

I prefer my LaTeX workflow where I can edit markup in Emacs, and have a preview almost instantly generated next to my editor by a filesystem watcher & makefile. TeXmacs necessitates using its own interface (which lacks my vim keybindings and Emacs customizations) and I could not find many resources on editing TeXmacs documents in external programs.

I did appreciate that the general typesetting in TeXmacs was high quality, and the ability to type TeX macros and get e.g. enumerated lists quickly was very nice. But overall, I prefer LaTeX.